Non-Steroidal Anti-Inflammatory Agents

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

Also Known As:

NSAIDs; Anti-Inflammatory Agents, Non-Steroidal; Anti Inflammatory Agents, Nonsteroidal; Antiinflammatory Agents, Non Steroidal; Antiinflammatory Agents, Nonsteroidal; Nonsteroidal Anti-Inflammatory Agents; Agent, Aspirin-Like; Agent, Non-Steroidal Anti-Inflammatory; Agent, Nonsteroidal Anti-Inflammatory; Anti-Inflammatory Agent, Non-Steroidal; Anti-Inflammatory Agent, Nonsteroidal; Anti-Inflammatory Analgesics; Aspirin Like Agent; Aspirin Like Agents; Non Steroidal Anti Inflammatory Agent; Non Steroidal Anti Inflammatory Agents; Nonsteroidal Anti Inflammatory Agent; Nonsteroidal Anti Inflammatory Agents; Nonsteroidal Antiinflammatory Agents; Analgesics, Anti-Inflammatory; Aspirin-Like Agent; Aspirin-Like Agents; NSAID; Non-Steroidal Anti-Inflammatory Agent; Nonsteroidal Anti-Inflammatory Agent

Chemical Actions and Uses
- Pharmacologic Actions: 164
  - Therapeutic Uses: 49043
    - Antirheumatic Agents: 5363
      - Non-Steroidal Anti-Inflammatory Agents: 17077
    - Anti-Inflammatory Agents: 4344
      - Non-Steroidal Anti-Inflammatory Agents: 17077
  - Physiological Effects of Drugs: 1
    - Peripheral Nervous System Agents: 5
      - Sensory System Agents
        Analgesics: 41572
        Non-Narcotic Analgesics: 887
        Non-Steroidal Anti-Inflammatory Agents: 17077

L McCullough Selected Research

L McCullough Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure